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[177Lu]Lu-NA-ET1
- Development stage
- Unknown
- Lead developer
- University of Nebraska Medical Center
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Beta-minus Emitters → Radiopharmaceuticals, Gamma Emitters → Radiopharmaceuticals
01
Overview
[177Lu]Lu-NA-ET1: sourced facts only. name: "Using this approach, we reported [177Lu]Lu-NA-ET1, an NTSR1-targeted construct." [PMID:40101018]; target: "Using this approach, we reported [177Lu]Lu-NA-ET1, an NTSR1-targeted construct." [PMID:40101018]; developer: "Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, 985830 Nebraska Medical Center, Omaha, Nebraska 68198, United States." [PMID:40101018]; modality: "Our laboratory is exploring the utilization of covalent cysteine protease inhibitors (e.g., E-64) to increase tumor retention of targeted radionuclide therapeutics (TRTs) through protein adduct formation." [PMID:40101018]; stage: "In this work, we continue the exploration of [177Lu]Lu-NA-ET1 in three different NTSR1-positive cancer models." [PMID:40101018]
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